ea0090oc9.5 | Oral Communications 9: Adrenal and Cardiovascular Endocrinology 2 | ECE2023
Kemkem Yasmine
, Santambrogio Alice
, Montibus Bertille
, Willis Thea
, Kaufman-Cook James
, Lodge Emily
, Yianni Val
, J. Oakey Rebecca
, L. Andoniadou Cynthia
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumours, which arise from neural crest (NC)-derived structures: the adrenal medulla and the paraganglia. Around one third of PPGLs are associated with inherited cancer susceptibility genes, the highest rate among all tumour types. Currently, the only diagnostic criterion for malignant disease is the presence of metastasis and no molecular or histological features have been identified that help predict risk. A...